diff --git a/README.md b/README.md
index ccb444d..08f414d 100644
--- a/README.md
+++ b/README.md
@@ -114,6 +114,8 @@ It's possible to modify the transpose configuration file, `STORE_PATH/transpose.
 ```
 transpose config add "NewEntry" "/path/to/location"
 transpose config get "NewEntry"
+transpose config disable "NewEntry"
+transpose config enable "NewEntry"
 transpose config list
 transpose config remove "NewEntry"
 transpose config update "NewEntry" "path" "/path/to/new/location"
diff --git a/src/transpose/console.py b/src/transpose/console.py
index 6af4213..d345ecd 100644
--- a/src/transpose/console.py
+++ b/src/transpose/console.py
@@ -34,6 +34,12 @@ def run(args, config_path) -> None:
         if args.config_action == "add":
             t.config.add(args.name, args.path)
             t.config.save(config_path)
+        elif args.config_action == "disable":
+            t.config.disable(args.name)
+            t.config.save(config_path)
+        elif args.config_action == "enable":
+            t.config.enable(args.name)
+            t.config.save(config_path)
         elif args.config_action == "get":
             print(t.config.get(args.name))
         elif args.config_action == "list":
@@ -115,7 +121,7 @@ def parse_arguments(args=None):
     apply_all_parser.add_argument(
         "--force",
         dest="force",
-        help="If original path already exists, existing path to <path>.backup and continue",
+        help="Continue with apply even if original path already exists or entry is disabled in config",
         action="store_true",
     )
 
@@ -128,7 +134,12 @@ def parse_arguments(args=None):
         "name",
         help="The name of the stored entity to restore",
     )
-    restore_parser.add_argument("--force", dest="force", action="store_true")
+    restore_parser.add_argument(
+        "--force",
+        dest="force",
+        help="Continue with restore even if original path already exists or entry is disabled in config",
+        action="store_true",
+    )
 
     store_parser = subparsers.add_parser(
         "store",
@@ -169,6 +180,26 @@ def parse_arguments(args=None):
         help="The path of the directory that should be symlinked to the store",
     )
 
+    config_disable_parser = config_subparsers.add_parser(
+        "disable",
+        help="Disable an entry within the config",
+        parents=[base_parser],
+    )
+    config_disable_parser.add_argument(
+        "name",
+        help="The name of the entry the config",
+    )
+
+    config_enable_parser = config_subparsers.add_parser(
+        "enable",
+        help="enable an entry within the config",
+        parents=[base_parser],
+    )
+    config_enable_parser.add_argument(
+        "name",
+        help="The name of the entry the config",
+    )
+
     config_get_parser = config_subparsers.add_parser(
         "get",
         help="Retrieve the settings of a specific entity, such as the path",
diff --git a/src/transpose/transpose.py b/src/transpose/transpose.py
index 20ab575..e4048fa 100644
--- a/src/transpose/transpose.py
+++ b/src/transpose/transpose.py
@@ -17,6 +17,7 @@ class TransposeEntry:
     name: str
     path: str
     created: str  # Should be datetime.datetime but not really necessary here
+    enabled: bool = True
 
 
 @dataclass
@@ -48,6 +49,36 @@ class TransposeConfig:
             created=created,
         )
 
+    def disable(self, name: str) -> None:
+        """
+        Disable an entry by name. This ensures actions are not run against this entry, such as apply and restore
+
+        Args:
+            name: The name of the entry (must exist)
+
+        Returns:
+            None
+        """
+        try:
+            self.entries[name].enabled = False
+        except KeyError:
+            raise TransposeError(f"'{name}' does not exist in Transpose config entries")
+
+    def enable(self, name: str) -> None:
+        """
+        Enable an entry by name
+
+        Args:
+            name: The name of the entry (must exist)
+
+        Returns:
+            None
+        """
+        try:
+            self.entries[name].enabled = True
+        except KeyError:
+            raise TransposeError(f"'{name}' does not exist in Transpose config entries")
+
     def get(self, name: str) -> TransposeEntry:
         """
         Get an entry by the name
@@ -105,11 +136,14 @@ class TransposeConfig:
         config = TransposeConfig()
         try:
             for name in in_config["entries"]:
+                entry = in_config["entries"][name]
                 config.add(
                     name,
-                    in_config["entries"][name]["path"],
-                    created=in_config["entries"].get("created"),
+                    entry["path"],
+                    created=entry.get("created"),
                 )
+                if "enabled" in entry and not entry["enabled"]:
+                    config.disable(name)
         except (KeyError, TypeError) as e:
             raise TransposeError(f"Unrecognized Transpose config file format: {e}")
 
@@ -162,7 +196,11 @@ class Transpose:
         if not self.config.entries.get(name):
             raise TransposeError(f"Entry does not exist: '{name}'")
 
-        entry_path = Path(self.config.entries[name].path)
+        entry = self.config.entries[name]
+        if hasattr(entry, "enabled") and not entry.enabled and not force:
+            raise TransposeError(f"Entry '{name}' is not enabled in the config")
+
+        entry_path = Path(entry.path)
         if entry_path.exists():
             if force:  # Backup the existing path
                 move(entry_path, entry_path.with_suffix(".backup"))
@@ -190,7 +228,11 @@ class Transpose:
         if not self.config.entries.get(name):
             raise TransposeError(f"Could not locate entry by name: '{name}'")
 
-        entry_path = Path(self.config.entries[name].path)
+        entry = self.config.entries[name]
+        if hasattr(entry, "enabled") and not entry.enabled and not force:
+            raise TransposeError(f"Entry '{name}' is not enabled in the config")
+
+        entry_path = Path(entry.path)
         if entry_path.exists():
             if force:  # Backup the existing path
                 move(entry_path, entry_path.with_suffix(".backup"))
diff --git a/tests/test_console.py b/tests/test_console.py
index 950f5ad..9b5f2ad 100644
--- a/tests/test_console.py
+++ b/tests/test_console.py
@@ -184,6 +184,26 @@ def test_run_config_add():
     assert config.entries.get(args.name)
 
 
+@setup_restore()
+def test_run_config_disable():
+    args = RunConfigArgs("disable")
+
+    run_console(args, TRANSPOSE_CONFIG_PATH)
+    config = TransposeConfig().load(TRANSPOSE_CONFIG_PATH)
+
+    assert config.entries[args.name].enabled is False
+
+
+@setup_restore()
+def test_run_config_enable():
+    args = RunConfigArgs("enable")
+
+    run_console(args, TRANSPOSE_CONFIG_PATH)
+    config = TransposeConfig().load(TRANSPOSE_CONFIG_PATH)
+
+    assert config.entries[args.name].enabled is True
+
+
 @setup_restore()
 def test_run_config_get(capsys):
     args = RunConfigArgs("get")
diff --git a/tests/test_transpose.py b/tests/test_transpose.py
index a147a98..8e1a090 100644
--- a/tests/test_transpose.py
+++ b/tests/test_transpose.py
@@ -52,11 +52,26 @@ def test_apply():
     assert TARGET_PATH.is_symlink()
     assert ENTRY_STORE_PATH.is_dir()
 
+    # Target is disabled in the config
+    t.config.entries[ENTRY_NAME].enabled = False
+    with pytest.raises(
+        TransposeError, match=f"Entry '{ENTRY_NAME}' is not enabled in the config"
+    ):
+        t.apply(ENTRY_NAME)
+
 
 @setup_restore()
 def test_restore():
     t = Transpose(config_path=TRANSPOSE_CONFIG_PATH)
 
+    # Target is disabled in the config
+    t.config.entries[ENTRY_NAME].enabled = False
+    with pytest.raises(
+        TransposeError, match=f"Entry '{ENTRY_NAME}' is not enabled in the config"
+    ):
+        t.restore(ENTRY_NAME)
+    t.config.entries[ENTRY_NAME].enabled = True
+
     # Success
     t.restore(ENTRY_NAME)
     assert TARGET_PATH.is_dir()
@@ -125,6 +140,28 @@ def test_config_add():
     assert config.entries["NewEntry"].path == str(TARGET_PATH)
 
 
+@setup_store()
+def test_config_disable():
+    config = TransposeConfig.load(TRANSPOSE_CONFIG_PATH)
+
+    with pytest.raises(TransposeError, match="'UnknownEntry' does not exist"):
+        config.disable("UnknownEntry")
+
+    config.disable(ENTRY_NAME)
+    assert config.entries[ENTRY_NAME].enabled is False
+
+
+@setup_store()
+def test_config_enable():
+    config = TransposeConfig.load(TRANSPOSE_CONFIG_PATH)
+
+    with pytest.raises(TransposeError, match="'UnknownEntry' does not exist"):
+        config.enable("UnknownEntry")
+
+    config.enable(ENTRY_NAME)
+    assert config.entries[ENTRY_NAME].enabled is True
+
+
 @setup_store()
 def test_config_get():
     config = TransposeConfig.load(TRANSPOSE_CONFIG_PATH)
diff --git a/tests/utils.py b/tests/utils.py
index 8d993c9..5026feb 100644
--- a/tests/utils.py
+++ b/tests/utils.py
@@ -26,11 +26,13 @@ TRANSPOSE_CONFIG = {
             "name": ENTRY_NAME,
             "path": str(TARGET_PATH),
             "created": "2023-01-21 01:02:03.1234567",
+            "enabled": True,
         },
         SECOND_ENTRY_NAME: {
             "name": SECOND_ENTRY_NAME,
             "path": str(SECOND_TARGET_PATH),
             "created": "2023-02-23 01:02:03.1234567",
+            "enabled": True,
         },
     },
 }